CDF is a three-letter acronym that may refer to:
Mathematics, science, and computers .cdf (formerly known as "AIA Format"), the ANDI/netCDF scientific data interchange file format Cation diffusion facilitator, transport protein Channel Definition Format, an XML standard Chip Description File, a genomic analysis file format Chlorinated dibenzofuran(s), a.k.a. polychlorinated dibenzofurans Cohen–Daubechies–Feauveau wavelet Collider Detector at Fermilab Comma-delimited format, now referred to as .csv (comma-separated values) Common Data Format, NASA software Composite Document File, a Microsoft compound document file format Compound Document Format, a set of W3C standards on a specific compound document format Computable Document Format, a format for interactive data visualizations Core Damage Frequency, a term used in probabilistic risk assessment for nuclear power plants Cumulative distribution function
Organizations California Department of Forestry and Fire Protection Canal del Fútbol (Chile) Children's Defense Fund (US) "Congregation for the Doctrine of the Faith (CDF)": former name of Dicastery for the Doctrine of the Faith (DDF) Crypto Developers Forum
Defence and military Ceylon Defence Force Chief of the Defence Force (disambiguation), position in multiple countries Chinland Defense Force, an insurgent group fighting against the State Administration Council (a military junta) in Chin State, Myanmar Ciskei Defence Force Civil Defence Forces, paramilitary organization in Sierra Leone
Development Constituency Development Fund Cooperative Development Foundation (US) Cooperative Development Fund Colonial Development Fund
Transport Cardiff Central railway station, National Rail station code CDF Cortina Airport, Italy (IATA code CDF)
Other CDF Croisières de France, a cruise ship operator Chesapeake Detention Facility Clostridioides difficile ESA's Concurrent Design Facility at ESTEC Congolese franc, the ISO 4217 code for the currency of the Democratic Republic of Congo Constructive developmental framework for psychological assessment Carlos Diego Ferreira, a Brazilian mixed martial artist Caspar David Friedrich, a German artist