GSC may refer to:
Business Game Show Central, an American TV network Global Security Challenge, a business competition Golden Screen Cinemas, in Malaysia Golden Star Resources, a Canadian gold mining company Good Smile Company, a Japanese manufacturer of hobby products GSC Enterprises, Inc., an American retailer and financial services company GSC Systems, a Canadian propeller manufacturer
Education Gainesville State College, now a campus of the University of North Georgia, in Oakwood, Georgia, United States Glasgow Science Centre, in Scotland Glassboro State College, now Rowan University, in Glassboro, New Jersey, United States Glenville State College, now Glenville State University, in Glenville, West Virginia, United States Global Studies Consortium, an international academic association Government Saadat College, in Karatia, Tangail, Bangladesh Government Science College (disambiguation) Granite State College, in New Hampshire, United States Greensboro Science Center, in North Carolina, United States
Entertainment Game Show Congress, a conference series Granite State Challenge, an American quizbowl television show The Great Space Coaster, an American children's television show Gunsmith Cats, a Japanese seinen manga GSC Game World, a Ukrainian video game developer Pokémon Gold, Silver and Pokémon Crystal
Government and military Air Force Global Strike Command, a major command of the United States Air Force General Secretariat of the Council of the European Union General Service Corps, of the British Army Geological Survey of Canada
Science and technology GSC (gene), encoding the goosecoid protein Global Standards Collaboration, in telecoms Genomic Standards Consortium Group switching centre, a former British telephone exchange GSC bus, a computer bus Guangzhou Science City, in Guangdong, China Guiana Space Centre, in French Guiana Guide Star Catalog, an astronomical catalogue Google Search Console, a webmasters' tool
Sports Game score, a baseball statistic Gezira Sporting Club, largest multi-sport facility in Egypt Ghana Super Cup, a football competition Girls' Sports Club, a women's sports club in Singapore 1929-1996 Glenmore Sailing Club, in Calgary, Alberta, Canada Goslarer SC 08, a German football club Gulf South Conference, a college athletic conference in the southeastern United States
Other uses Gascon language, spoken in France General Santos City, a city in the Philippines Glenwood Springs station, a railway station in Colorado, United States Greater Sylhet Development and Welfare Council in UK, a British charity Green Schools Campaign, a renewable energy campaign in Malaysia Guided Self-Change Girl Scout Cookies Gulf Stream Council, of the Boy Scouts of America