TLB may refer to:
Science and technology Adaptive transmit load balancing or balance-tlb, a Linux bonding driver mode Canon TLb, a 35 mm camera Translation lookaside buffer, a computer memory cache Turcicum Leaf Blight, also known as Northern corn leaf blight
Transport Atlas Atlantique Airlines (ICAO airline code), France Talybont railway station (National Rail station code), Gwynedd, Wales
Other uses Army Top Level Budget, the responsibility of the UK Deputy Chief of the General Staff The Living Bible, a personal paraphrase of the Bible