Cullis is a surname. Notable people with the surname include:
Anthony Cullis (1946–2021), a British electronic engineer Cuthbert Edmund Cullis (1868–1954), an English mathematician Eleanor Cullis-Hill (1913–2001), an Australian architect Kevin Cullis (born 1958), an English football manager Severn Cullis-Suzuki (born 1979), a Canadian environmental activist, speaker, television host, and author Stan Cullis (1916–2001), an English football player and manager Winifred Cullis (1875–1956), a British physician and academic