Itani is a surname. Notable people with the surname include:
Ahmad Itani (born 1979), Lebanese football player Frances Itani (born 1942), Canadian fiction writer, poet and essayist Junichiro Itani (1926–2001), anthropologist and founder of Japanese primatology Muhieddine Itani (1929–2015), Lebanese football player Munir Itani, Lebanese alpine skier and Olympian Ted Itani (1939–2021), retired Canadian military officer and humanitarian