Mercantile Building may refer to:
10 East 40th Street, 48-story, 193 m (632 ft) skyscraper, also referred to as the Mercantile Building, in Manhattan, New York Mercantile National Bank Building, 31-story, 159.4 m (523 ft) skyscraper at 1700 Main Street, Dallas, Texas Mercantile Continental Building, building located at 1810 Commerce Street, Dallas, Texas Sun Mercantile Building, warehouse building in Phoenix, Arizona Mercantile Building Society, defunct UK building society