Luis Vega may refer to:
Little Louie Vega (born 1965), American DJ, record producer and remixer Luis Vega Torres (born 1998), Cuban swimmer Luis Calderón Vega (1911–1989), Mexican politician and writer Luis Vega (mathematician) (born 1960), Spanish mathematician Luis de Vega, 16th-century Spanish architect Luis Lasso de la Vega, 17th-century Mexican priest and lawyer Luis Vega De Castro (born 1944), Cuban artist Luis Vega Ramos (born 1970), Puerto Rican lawyer and politician Luis Vega (footballer) (born 2002), Honduran footballer