Osseiran is an Arabic surname (Arabic: عسيران). Notable people with the surname include:
Osseiran family, a famous Lebanese family Adel Osseiran, Lebanese politician and statesman, a former Speaker of the Lebanese Parliament Ali Osseiran, Lebanese politician, MP and former Lebanese government minister Sheikh Mohamad Osseiran, Jaafari mufti of Saida and Zahrani districts of South Lebanon, Lebanon