Dipeptidyl-peptidase I

Dipeptidyl peptidase I () is an enzyme which in humans is encoded by the CTSC gene, and often called cathepsin C. This enzyme catalyses the following chemical reaction

Release of an N-terminal dipeptide, Xaa-Yaa!Zaa-, except when Xaa is Arg or Lys, or Yaa or Zaa is Pro

This Cl-dependent, lysosomal cysteine-type peptidase is maximally active at acidic pH.

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