Mastino may refer to: The rechristened name of the British boat Empire Becky
Dogs Mastino Napoletano, one of the names for the Neapolitan Mastiff breed of dog Software, is named after the dog Mastinaro/Mastinari are breeders of the dogs
Personas Bruiser Mastino, a wrestling persona performed by Mike Hallick and Glenn Jacobs Former member of the band Punkreas
People (born 1949), rector for the University of Sassari F. Mastino, midfielder for FC Baulmes Mastino della Scala: Mastino I della Scala (died 1277) Mastino II della Scala (1308–1351)