The Molise regional election of 1980 took place on 8 June 1980.

Events Christian Democracy was by far the largest party, gaining more than three times the share of vote of the Italian Communist Party, which came distantly second.

After the election Florindo D'Aimmo, the incumbent Christian Democratic President, was re-elected, but he was replaced by Giustino D'Uva in 1982 and later by Ulderico Colagiovanni in 1984.

Results Parties votes votes (%) seats Christian Democracy112,98555.417 Italian Communist Party32,04915.75 Italian Socialist Party19,1019.43 Italian Democratic Socialist Party9,7914.82 Italian Liberal Party8,3514.11 Italian Social Movement8,2614.11 Italian Republican Party7,5883.71 New Molisan Left2,5971.3- Proletarian Unity Party1,5560.8- Molisan Artisans Merchants 1,5530.8- Total203,832100.030 Source: Ministry of the Interior