Samuel M. Axford (died 1873) was an American politician and medical doctor who was the 11th mayor of Flint, Michigan.Chapter XIII: Roster of City Officials . The History of Genesee County, MI.

Early life Axford lived in his youth in Oakland County. He attended the University of Michigan for medical education. In 1858, he moved from Detroit to Flint.Chapter XVIII: Early Physicians & Medical Societies. The History of Genesee County, MI. He built Axford House as a joint residence and hospital.Private Hospitals: The Axford . 1809-1930: History of Hospitals in Michigan. Author: Karen Stevenson .

Political life He was elected as the eleventh mayor of the Village of Flint in 1868 serving a single 1-year term.

Axford died in 1873.

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