The Apulian regional election of 1980 took place on 8 June 1980.

Events Christian Democracy was by far the largest party, while the Italian Communist Party came distantly second. After the election Nicola Quarta, the incumbent Christian Democratic President, formed a new centre-left government (Organic Centre-left). In 1983 Quarta was replaced by Gennaro Trisorio Liuzzi, a Christian Democrat who had already served as President of the Region from 1970 to 1975.

Results Parties votes votes (%) seats Christian Democracy924,50242.122 Italian Communist Party540,05824.613 Italian Socialist Party291,60913.36 Italian Social Movement204,2409.35 Italian Democratic Socialist Party114,5705.22 Italian Republican Party54,5452.51 Italian Liberal Party35,5901.61 Proletarian Unity Party28,6981.31 Apulian Radical List1,8680.1- Revolutionary Communist League5290.0- Total2,125,780100.050 Source: Ministry of the Interior