One Way Out may refer to:
Music One Way Out (The Allman Brothers Band album), the 2004 live album by The Allman Brothers Band One Way Out (Melissa Etheridge album), 2021 "One Way Out" (song), the blues song recorded by Sonny Boy Williamson II, Elmore James, and The Allman Brothers Band
Arts and entertainment One Way Out (film), the 1955 British crime drama film starring Jill Adams and Eddie Byrne One Way Out (2002 film), a 2002 crime drama starring James Belushi One Way Out (TV series), the Discovery Channel TV series featuring escape artist Jonathan Goodwin "One Way Out" (Andor), TV episode One Way Out, a 2019 crime thriller novel by British Indian writer A A Dhand