Amyderýa Nature Reserve () is a nature reserve (zapovednik) of north-eastern Turkmenistan.

Established in 1982 to protect part of the Amu Darya River, it is located in the north-east of Lebap Province and covers an area of 495 km2.

It also incorporates one sanctuary: Kelif Sanctuary - established in 1970.

References National Program for the Protection of the Environment, Ashgabat, 2002, pp. 149–151

External links Amudarya State Nature Reserve on Nature Protection Amudarya State Reserve of Turkmenistan - Oriental Express Caucasus & Asia