De Felice, De Félice or DeFelice is a surname with Italian and Swiss origins.

De Felice, de Felice or de Félice Aurelio De Felice (1915–1996), Italian sculptor Emidio De Felice (1918–1993), Italian linguist and lexicographer Fabio De Felice (1927–2024), Italian politician Fortunato de Felice, 2nd Count Panzutti, (1723–1789), Italian physicist and encyclopedian Guillaume de Félice, 4th Count Panzutti, (1803–1871), Savoy theologian and abolitionist Jean-Jacques de Felice (1928–2008), French lawyer and human rights activist Lionello De Felice (1916–1989), Italian screenwriter and film director Renzo De Felice, (1929–1996), Italian historian of fascism various other Counts Panzutti

DeFelice Cynthia DeFelice (born 1951), American children's author Garth DeFelice, American football umpire Jonathan DeFelice, American monk and college president

See also Palazzo De Felice (disambiguation) DiFelice, a surname Felice (surname)

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