Crusius is a Latinized German surname, typically from the names Kraus or Krause. It may refer to:
Christian August Crusius (1715–1775), German philosopher and Protestant theologian Ludwig Friedrich Otto Baumgarten-Crusius (1788–1843), German Protestant divine Martin Crusius (1524–1607), German classicist, historian, and professor Otto Crusius (1857–1918), German classical scholar Patrick Crusius (born 1998), perpetrator of the 2019 El Paso Walmart shooting Yeda Crusius (born 1944), Brazilian politician
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