The following is a list of characters that first appeared in the Channel 4 soap opera Hollyoaks in 2006, in order of first appearance.

Amy Barnes

Mike Barnes

Mike Barnes is a fictional character from the soap opera Hollyoaks, played by famous Coronation Street actor, Tony Hirst.

Michaela McQueen

Ste Hay

Wayne Tunnicliffe

Wayne Tunnicliffe, played by Joe Marsden, made his first appearance in 2005. He was introduced as one of Ste Hay's friends. Ste was interested in Amy Barnes, while Wayne dated Michaela McQueen. Wayne was only interested in her because she was "easy" and after a few months he dumped her via text message.

Wayne and Ste befriended Josh Ashworth and his cousin Fletch to get close to Josh's sister Hannah Ashworth (they gave up because Hannah was always out with friends). A nastier moment arrived when Ste and Wayne began bullying Nicole Owen after her brother Sam blew up the Dog in the Pond. They eventually pretended to care about her, taking her to the woods, getting her drunk, and planning to rape her. She threw herself on the ground, sobbing and telling them to get on with it, and they left her alone.

Ste was sent to a juvenile detention facility for his part in a joyride which sent Amy to hospital. Wayne was next seen in spring 2007, hanging out with Sonny Valentine. Wayne soon discovered that his ex, Michaela, fancied Sonny so he mentioned it to Sonny, not knowing that he and Michaela were secretly going out. Wayne made fun of Michaela to Sonny behind her back and Sonny went along with it to keep their relationship a secret, but when Wayne went too far insulting Michaela, Sonny stood up to him and told him that he and Michaela were dating. Wayne also taunted her about her gay brother, John Paul McQueen, only for John Paul to grab him and threaten him into leaving Michaela alone.

Wayne began selling his little brother's ADD medication at school. Nancy Hayton, who needed pills to cope with her hectic life, began buying them. When Wayne ran out of medication, she lost her temper. Wayne promised her he would get more and he tried to ask Nancy out. Wayne got cinema tickets but Nancy ripped them up, enraged that Wayne would not get the drugs in time for her next exams.

Wayne was last seen at a house party thrown by Amy and Michaela. Wayne stole food and CDs and when Amy caught him in baby Leah's room, a drunk Wayne grabbed Leah as a hostage. Wayne's former mate Ste grabbed the baby and punched Wayne before throwing all the partygoers out of the house.

Sean Kennedy

Willamina Webster

Willamina Webster also known as Mrs. Webster was the head teacher at Hollyoaks High School. She spoke to Nancy Hayton when she was struggling in school due to her sister Becca Dean's murder, and later when Nancy accused of sexual harassment. Mrs. Webster's son Pete Webster worked as a teacher and sexually harassed Tina McQueen in October 2007. Tina told Mrs. Webster, who made her son apologise. Pete later tried to force himself on Tina, fired her, and was humiliated by her sister Jacqui McQueen. In January 2008, following Michaela McQueen's overdose, she performed a spot check of all the students' lockers for drugs. She almost uncovered Fletch's drugs in his locker, but was stopped by the fire alarm.

In June 2008 she was involved in the story about Josh and Michaela cheating in their coursework. They both eventually were suspended for a week. In addition, Sasha Valentine and Fletch stole her laptop to sell for drugs but it was eventually returned. During both of these events, Mrs Webster never made an appearance.

Mrs. Wesbter was not seen on-screen again because, in November 2008, Govinda Roy, the father of Ravi Roy, Ash Roy, Anita Roy and Leila Roy, debuted as the new headmaster at Hollyoaks High.

Myra McQueen

Mercedes McQueen

Warren Fox

Diane Valentine

Diane Valentine and her three children Calvin, Sonny and Sasha Valentine bought the home of Liz Burton and their arrival started off inauspiciously when they had to forcibly remove Liz's daughters Sophie and Mel Burton. Diane was proud of Calvin, although she was upset about his plans to leave home once he graduated from the police force. Sonny was involved in various criminal activities Diane knew nothing about. Sasha was the youngest of the family and coping with growing up.

Diane's stay in town was short-lived, on her way to her car, she dropped her keys. When she bent over to pick them up, she didn't see Jake Dean's car driving towards her and she was hit and killed.

Diane's death shattered her family, as her husband Leo Valentine showed up to try to pick up the pieces and keep the family together.

Calvin Valentine

Sasha Valentine

Sonny Valentine

Eddie Griffiths

Edward "Eddie" Griffiths was played by actor and musician Che Watson from 2006 to 2010

Eddie is a police officer and works alongside Calvin Valentine. Eddie first appeared in 2006, when Calvin was going to move in with him. Calvin then decided not to after the death of his mother. In 2008, Eddie found drugs in Calvin's coat pocket after seeing him with Nige. The following day, Eddie confronted Calvin and told him that he was going to report him to Superintendent Lacey, but Calvin later convinced him not to.

He returned on 15 September 2008, during a routine search of The Loft. On 5 February 2009, it was revealed that he had been promoted to sergeant, although on 6 April 2010 he wore a Constable's uniform.

Tina Reilly

Leo Valentine

Carmel McQueen

Foz

"Foz" was the boyfriend of Nancy Hayton. He is a tattooist and was working in a tattoo parlour when Nancy met him. Foz is a counter-stereotype; although heavily tattooed and pierced, he is actually philosophical, peaceful and artistic. He painted a 'realistic' memorial to those who died in The Dog fire, to the dismay of the bereaved Justin Burton. After losing the premises to his tattoo parlour, Foz decided to go back to college and he became a part-time lecturer and MA student at Hollyoaks Community College. He has a free spirited New Age mother (Willow) who made a brief appearance. According to Willow, she spent Foz's childhood taking him touring round circus and women's camps.

As of 2 January 2007, Foz has left Hollyoaks as a result of a higher calling; to serve and assist the impoverished of Goa. Nancy had agreed to go with him, but changed her mind at the last minute. They said they loved each other, and Foz said maybe he'd run into her somewhere in the world someday. His final words were, "Take care."

Kris Fisher

Zoe Carpenter

Will Hackett

John Paul McQueen

Jacqui McQueen

Davey Thomas

"Davey Thomas" was the boyfriend of a con Jacqui McQueen met in prison. He first appeared when he demanded £10,000 from Jacqui which she had got from a men's public bathroom after doing a favour for her mate in prison with help from her sister Mercedes. On their way out they accidentally dropped the vase the money was in which meant them taking the money back to their house. When Carmel McQueen found out about the money she stole £4,000 of the money to get her boobs done. When Davey found out about this he demanded his other £6,000. Mercedes' boyfriend Russ Owen and Jacqui's mother Myra McQueen gave him what they had, but it was still not enough. Several months later, he returned, demanding Jacqui marry Albanian immigrant Aleksander Malota. Jacqui refused, but eventually gave in. On her wedding day, she again changed her mind, but Davey showed up at the wedding. During a fight with Jacqui's boyfriend Tony Hutchinson, Jacqui knocked Davey out, but when he woke up, he informed her that they were both now in debt to very powerful people who would hurt her and her family. Jacqui relented and married Aleksander. When they split up several months later, with Aleksander returning to Albania, there were no apparent consequences.

Ricky Bowen

Richard "Ricky" Bowen is the father of McQueen siblings Carmel and Michaela McQueen. Ricky had a relationship with Myra McQueen and became stepfather to her three daughters Jacqui, Mercedes, and Tina. Ricky went on to have two more children with Myra, daughters Carmel and Michaela. While he was away with his band, Myra slept with Iain Naimsmith, before Iain began his transition to being a woman named Sally St. Claire. When Rickey returned Myra lied to Ricky and John Paul and said John Paul was Ricky's son. After youngest daughter Michaela was born, Ricky left Myra and the children for their next door neighbour, 17-year-old daughter Heather McCallister, who later gave birth to his son Richard. Ricky came in and out his children's lives. Carmel and John Paul learned not to trust their father, but Michaela wanted a chance to get to know him. She managed to get Ricky's number and he came to visit her. He told her he wanted to make up for the past, but while they were alone in the house, Ricky convinced Michaela to go out to the store. While she was gone, Ricky stole the family's Christmas gifts, liquor, and television, leaving Michaela heartbroken.

Charlie Dean

Charlie Dean (also Osborne), played by Charlie Behan between 2011 and 2026, is the son of Becca Hayton (Ali Bastian) and Justin Burton (Chris Fountain), Becca gave birth to him after being sentenced to imprisonment after alleged under-age activity with Justin. After Charlie was born, it was unknown whether Justin or her husband Jake Dean (Kevin Sacre) was his father. Becca originally gave Charlie to Jake, but when Justin firsts meets Charlie after stealing Jake's car Justin realizes he is the father. Jake's sister Steph Dean (Carley Stenson) convinced Jake to take a paternity test in January 2007, but Jake destroys the results and assumed the role of Charlie's father, along with his wife and Becca's sister, Nancy Hayton (Jessica Fox). In February 2007, Becca was stabbed in prison, and dies afterwards, and Charlie never got a chance to see her.

In August 2024, it was reported that Behan had left Hollyoaks, The news came amid the announcements that several other cast members would be leaving the soap due to Hollyoaks having to reduce the number and duration of their weekly episodes. Some viewers expressed unhappiness and confusion on social media over the news of Behan's departure. His final appearance aired in the episode originally released on 11 September 2024. In November 2024, it was announced that Behan would return to the soap for a guest stint later that month. In September 2025, it was reported that Behan would reprise the role again on Hollyoaks later that month. Behan also portrayed Charlie in the Hollyoaks late-night special Hollyoaks Later for the soap's 30th anniversary, which was broadcast on 22 October of that year. The character was later written out again and Behan's exit aired on 8 June 2026, when Charlie was arrested for his role in a car crash.

In May 2006, Becca discovered that she was pregnant but was unaware of whether the father was Jake or Justin, whom she had been having an affair with. She initially kept the pregnancy from Justin, and let Jake believe that he was Charlie's father. However, in July 2006, Becca and Justin's affair was revealed and Jake realised that he may not be the father.

Becca chose Justin over Jake, but later changed her mind and went back to Jake, deciding that Jake would be the father, regardless of the paternity. Justin reported Becca to the police for their affair, and lied that they had begun a sexual relationship when Justin was 15. Becca was arrested and imprisoned, but in December 2006, she went into labour at her sentencing and gave birth to a son in hospital. She named the baby Charles, nicknaming him Charlie. Charlie stayed with Becca in prison. Justin eventually admitted to lying, and Becca was released. However, in February 2007, on the day she was released, Becca was stabbed by Fran Hathaway and she died in hospital.