William Arthur Karns (December 28, 1875 – November 15, 1941) was an American Major League Baseball (MLB) pitcher. Karns played for the Baltimore Orioles in . In 3 career games, he had a 1–0 record, with a 6.35 ERA. He batted and threw left-handed.
Karns was born in Richmond, Iowa, and died in Seattle, Washington.
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