is a Japanese surname. Notable people with the surname include:
Aki Yaguchi, a Japanese/Australian artist Mari Yaguchi (born 1983), a Japanese pop singer Masaaki Yaguchi (born 1979), guitarist for the Japanese rock band called Mucc Shinobu Yaguchi (born 1967), a Japanese film director and screenwriter Yoko Yaguchi (1921–1985), a Japanese actress, and the wife of Japanese filmmaker Akira Kurosawa for 39 years Yukihiko Yaguchi (born 1955), a Japanese car designer Yutaka Yaguchi (1932–2023), a martial artist