Lydon is a surname of Irish origin, an anglicization of "Loideán", and may refer to:
Alexander Francis Lydon (1836–1917), English engraver of natural history Alexandra Lydon (born 1979), Irish and American television actress Christopher Lydon (born 1940), American media personality and author Don Lydon (born 1938), Irish psychologist and former politician in Ireland Gary Lydon (1964–2026), British-born Irish actor James Francis Lydon (1928–2013), Irish historian Jimmy Lydon (1923–2022), American movie actor and television producer Joe Lydon (1878–1937), American welterweight boxer Joe Lydon (born 1963), English rugby league footballer and rugby union coach John Lydon (born 1956) also known as Johnny Rotten, British rock musician Joseph Patrick Lydon (1878–1937), American welterweight boxer William A. Lydon (1863–1918), founded the Great Lakes Dredge and Dock Company