John Cheyne may refer to:

Sir John Cheyne (speaker) (died 1414), speaker of the House of Commons John Cheyne (MP for Buckinghamshire) (died c.1447), member of parliament (MP) for Buckinghamshire, 1413, 1415, 1425 and 1427 Sir John Cheyne (builder of Chenies Manor) in Chenies, Buckinghamshire c.1460 Sir John Cheyne (died 1467), (1410–1467), MP for Kent Sir John Cheyne (died 1468) (c.1390–1468), MP for Buckinghamshire, 1421 to 1445 John Cheyne (died 1585), MP for Chipping Wycombe John Cheney (gentleman at arms) (died 1567), MP for Dover, Winchelsea and Berkshire John Cheyne, Baron Cheyne (c. 1442–1499), Master of the Horse to Edward IV of England John Cheyne (physician) (1777–1836), British physician, surgeon and author Sir John Cheyne (advocate) (1841–1907), Scottish advocate

See also John Cheney (disambiguation) John Chaney (disambiguation)