The GCSE is the General Certificate of Secondary Education, a British qualification (introduced 1986).
GCSE can also refer to: "Ghetto Children Sex Education", a 2005 hip-hop single by Blak Twang Global common subexpression elimination, in computer science Grand Cross of the Saxe-Ernestine House Order, Germany (1833–1981) Grand Cross of the Military Order of Saint James of the Sword, Portugal