Inspired by the terms genome and genomics, other words to describe complete biological datasets, mostly sets of biomolecules originating from one organism, have been coined with the suffix -ome and -omics. Some of these terms are related to each other in a hierarchical fashion. For example, the genome contains the ORFeome, which gives rise to the transcriptome, which is translated to the proteome. Other terms are overlapping and refer to the structure and/or function of a subset of proteins (e.g. glycome, kinome).
An omicist is a scientist who studies omeomics, cataloging all the "omics" subfields.
Omics.org is a Wiki that collects and alphabetically lists all the known "omes" and "omics."
List of topics -ome Field of study(-omics) Collection of Parent subject NotesAcetylomeAcetylomicscomplete set of proteins and their corresponding lysine residues that undergo acetylationMolecular BiologyAllergenome Allergenomics Proteomics of allergens GeneticsAntibodyomeAntibodyomicsThe complete set of antibodies present in an organismImmunologyArchaeomeArchaeomicsThe collective genetic material of microorganisms in archaeological samplesMicrobiologyBacteriomeBacteriomicsCommunity of bacteria associated with a particular ecological niche or host organismMicrobiologyBibliome Bibliomics Scientific bibliographic data BiointeractomeBiointeractomicsThe complete set of molecular interactions within a biological systemMolecular BiologyBiomeThe whole set of ecological community of organisms and environmentsEcologyCellomeCellomicsCellular BiologyConnectome Connectomics Structural and functional brain connectivity at different spatiotemporal scales Neuroscience Cytome Cytomics Cellular systems of an organism Cytology Editome RNA editing sites Embryome Embryomics Cell lineages of embryonic cells, genes expressed and antigens present during development Embryology Envirome Enviromics Gene related environment factors (envirome) Environmental DNA Environmental omics Sequencing of ambient DNA Epigenome Epigenomics Epigenetic modifications Molecular genetics Epigenomics is the study of the complete set of epigenetic modifications on the genetic material of a cell, collectively known as the epigenomeExposome (2005) Exposomics An individual's environmental exposures, including in the prenatal environment Molecular genetics A proposed term and field of study of the disease-causing effects of environmental factors (the "nurture" component of "nature vs. nurture").Exposome (2009) Composite occupational exposures and occupational health problems Occupational safety and health The proposers of this term were aware of the previous term as used above but proposed to apply the term to a new field.Exome Exomics Exons in a genome Molecular Genetics Foodome Foodomics Food and Nutrition issues related to bioactivity, quality, safety and traceability of foods through the application and integration of advanced omics technologies to improve consumer's well-being, health, and confidence. Nutrition The term was first defined in 2009 Functional genomics gene (and protein) functions and interactions Molecular Biology Genome Genomics(Classical genetics) Genes (DNA sequences/Chromosomes) Genetics "Genome" refers to the set of all genes in an organism. However, "genome" was coined decades before it was discovered that most DNA is "non-coding" and not part of a gene; thus, "genome" originally referred to the entire collection of DNA within an organism. Today, both definitions are used, depending on the context.Glycome Glycomics Glycans Glycobiology HologenomeHologenomicsGenomes of community members (i.e., holobionts)MetagenomicsHumeomeHumeomicsThe chemical components of soil humusSoil scienceInterferome Interferomics Interferons Immunology Also a database of the same name.Interactome Interactomics All interactions The term "interactomics" is generally not used. Instead, interactomes are considered the study of systems biology.Ionome Ionomics Inorganic biomolecules Molecular Biology Kinome Kinomics Kinases Molecular Biology Proteins that add a phosphate groupLipidome Lipidomics Lipids Biochemistry Mechanome Mechanomics The mechanical systems within an organism Metabolome Metabolomics Metabolites All products of a biological reaction (including intermediates)Metagenome Metagenomics Genetic material found in an environmental sample Molecular Biology The genetic material is assumed to contain DNA from multiple organisms and therefore multiple genomes, hence the inclusion of the prefix meta-.Metallome Metallomics Metals and metalloids Microbiome microbiomics Collection of microorganisms in another organism such as an animal MicrobiologyObesidome Obesidomics Obesity related proteins Proteomics Coined by Pardo et al., 2012.ORFeome ORFeomics Open reading frames (ORFs) Molecular Genetics Organome Organomics Organ interactions Cellular Signalling / Cell Signaling and Tissue Engineering The study of crosstalk between organs using physiologically relevant in-vitro modelsParvome Parvomics Secondary metabolites Biochemistry Coined by Mark Martin and introduced by Julian Davies in 2008, referring to the Latin parvus for "small", and describing the "humungous microbial world of small (secreted) molecules of great structural diversity". See also Pharmacogenetics Pharmacogenetics SNPs and their effect on pharmacokinetics and pharmacodynamics PharmacogenomicsGenomics Pharmacogenome Pharmacogenomics The effect of changes on the genome on pharmacology PharmacogeneticsGenomics Phenome Phenomics Phenotypes Genetics Physiome Physiomics Physiology of an organism Phytochemome Phytochemomics Phytochemicals The term has been coined by del Castillo et al., 2013, Food Research International . Phytochemomics is a comprehensive concept aimed to increase the knowledge of phytochemicals' bioactivity which is of growing importance in agricultural, food, medicine and cosmetic sciencesProteome Proteomics Proteins Molecular Biology Regulome Regulomics Transcription factors and other molecules involved in the regulation of gene expression Molecular Biology Researchsome Research areas covered by an individual researcher or institution Research Coined by Ivan Erill at the 2011 EBM meeting(2011) "15th EBM PROGRAM" Evolutionary Biology Meeting at Marseilles. Retrieved December 14, 2011.Secretome Secretomics Secreted proteins Proteomics Subset of the proteome consisting of proteins actively exported from cells.Speechome Speecheomics Influences on language acquisition Coined by the Human Speechome ProjectBBC article on the Speechome ProjectSynthetome A set of artificial genes in an organism SynthetomeTranscriptome Transcriptomics All RNA molecules including mRNA, rRNA, tRNA and other ncRNAs Molecular Biology TrialomeMedicineHuman interventional trials data from clinical trial registries extended with trial results and links to resulting publicationsToponome Toponomics Cell and tissue structure Molecular BiologyViromeViromicscomplete set of virusesVirologyVolatilome Volatilomics complete collection of volatile metabolites Biomarkers
Hierarchy of topics For the sake of clarity, some topics are listed more than once.
Of biomolecules (moleculome):
Antibodyome Epigenome Methylome Genome Variome Exome ORFeome Transcriptome Editome Pharmacogenome Regulome Hologenome Metagenome Interferome (interferon-regulated genes) Membranome Metallome Glycome Ionome Lipidome Metabolome Volatilome Metallome Proteome Acetylome – post-transcriptional modification Kinome Secretome Chaperome Allergenome
Of molecule-molecule interactions:
Interactome (between large molecules) Fluxome (between large molecules and their [mainly small] substrates)
Of parts of an organism, or characteristics of it:
Cytome Embryome Obesidome Organome Phenome Physiome Connectome Synaptome Dynome Mechanome Regulome Toponome
Of the broader environment (Exposome):
Envirome Toxome Foodome Biome - Microbiome Sociome
Of man-made objects:
Bibliome Researchsome Trialome
References