RDI may refer to:

Organisations Ici RDI, formerly Réseau de l'information, a Canadian French language news channel owned by Radio-Canada Rassemblement démocratique pour l'indépendance, unofficial banner of dissident deputies of Parti Québécois in 1984–1985 RDI Video Systems, a video game company Renew Democracy Initiative, an American political organization promoting and defending liberal democracy Resource Development International, Louisville, Kentucky organization that works on water, sanitation, education, and community development projects Response Dynamics, a conservative direct marketing firm Rural Development Institute, Canadian research center

Science and technology Radar Doppler à Impulsions, air intercept radar on French Mirage 2000C fighters that was developed from the Radar Doppler Multifunction Reference Daily Intake or Recommended Daily Intake, a quantity of recommended nutrient intake Relationship Development Intervention, a treatment for autism Resistance Database Initiative, a not-for-profit HIV/AIDS research organisation Respiratory disturbance index, a tool for measuring frequency of breathing related sleep disturbances RDI register, a 64-bit processor register of x86 CPUs Reflected DOM Injection, an XSS technique

Other Royal Designers for Industry, a British honour bestowed on leading designers by the Royal Society of Arts