Rustam Khan may refer to:
Rostom of Kartli, a Georgian vali/king Rustam Khan Zand, a Zand dynasty prince. Rostam Khan (sepahsalar under Safi), a Safavid general of Georgian origin Rostam Khan (sepahsalar under Suleiman I), Safavid general of Georgian origin Prince Rostom of Kartli, 18th-century Georgian royal who served in the Safavid ranks Rostam Khan Judaki, a village in Iran RostamKhan, Ilam, a village in Iran