Francis I or Francis the First may refer to:
People Kings and emperors
Francis I of France (1494–1547), King of France, reigned 1515–1547 Francis I, Holy Roman Emperor (1708–1765), reigned 1745–1765 Francis II, Holy Roman Emperor, also known as Francis I, Emperor of Austria, (1768–1835), reigned 1804–1835 Francis I of the Two Sicilies (1777–1830), reigned 1825–1830
Dukes Francis I, Duke of Brittany (1414–1450), reigned 1442–1450 Francis I, Duke of Saxe-Lauenburg (1510–1581), reigned 1543–1571 Francis I, Duke of Nevers (1516–1561), reigned 1539–1561 Francis I, Duke of Lorraine (1517–1545), reigned 1544–1545 Francesco I de' Medici, Grand Duke of Tuscany (1541–1587), reigned 1574–1587 Francesco I d'Este, Duke of Modena (1610–1658), reigned 1644–1658
Others Francesco I Gonzaga (1366–1407) Francis I of Beauharnais (died 1587), leading noble of the French House of Beauharnais Francis I Rákóczi (1645–1676), elected prince of Transylvania Francis I (Erbach-Erbach) (1754–1823), Count of Erbach Franz I, Prince of Liechtenstein (1853–1938) Pope Francis (1936–2025), leader of the Catholic Church from 2013 to 2025
Media Francis the First (play), an 1832 play by Fanny Kemble Francis the First (film), a 1937 French historical comedy film Francis the First, an opera composed by Edward Loder
See also Francesco I (disambiguation) Francisco I. Madero (1873–1913), Mexican revolutionary, writer and statesman; 37th president of Mexico Franz Joseph I, Prince of Liechtenstein Franz Joseph I of Austria