Wycombe may refer to the following places:
Australia Wycombe, Queensland, a locality in the Maranoa Region High Wycombe, Western Australia, a suburb of Perth
United Kingdom High Wycombe, Buckinghamshire, England Wycombe District, a local government district Wycombe Rural District, a former local government district Wycombe (UK Parliament constituency)
United States Wycombe, Pennsylvania, a village in Wrightstown Township, United States
See also Wickham (disambiguation) Wykeham (disambiguation) Wycomb, Leicestershire, England