Cross syndrome (also known as Cross–McKusick–Breen syndrome, hypopigmentation and microphthalmia, and oculocerebral-hypopigmentation syndrome) is an extremely rare disorder characterized by white skin, blond hair with yellow-gray metallic sheen, small eyes with cloudy corneas, jerky nystagmus, gingival fibromatosis and severe intellectual disability and physical retardation.James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. .

It was characterized in 1967.

See also Oculocerebrocutaneous syndrome List of cutaneous conditions

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