Antonio Smith may refer to:
Antonio Smith (artist) (1832–1877), Chilean landscape painter and caricaturist Antonio Smith (athlete) (born 1967), Venezuelan hurdler Antonio Smith (defensive end) (born 1981), American football defensive end Antonio Smith (cornerback) (born 1984), American football cornerback Antonio Arnelo Smith, involved in an alleged police brutality incident in Valdosta, Georgia, in 2020 Antonio Smith (basketball), university basketball player from Flint, Michigan
See also Tony Smith (disambiguation)