Malkiel is both a given name and a surname. Notable people with the name include:

Malkiel Ashkenazi, 16th-century Ottoman rabbi Malkiel Gruenwald, Israeli hotelier, journalist, and stamp collector Malkiel Kotler, Rosh Yeshiva of Beth Medrash Govoha Burton Malkiel (born 1932), American economist and writer Yakov Malkiel (1914–1998), Russian-born American etymologist and philologist