William Patton may refer to:
William Patton (preacher) (1798–1879), American preacher William Weston Patton (1821–1899), his son, American abolitionist William Hampton Patton (1853–1918), American entomologist
William Patton (architect), English-born, American architect of churches including Church of Our Saviour (Placerville, California) Will Patton (born 1954), American actor Billy Joe Patton (1922–2011), American amateur golfer
See also William Patten (disambiguation) William Paton (disambiguation) William Patton Thornton (1817–1883), American physician and educator