John Wayne Kappler (born December 22, 1943, in Baltimore, Maryland) is a professor in the Department of Integrated Immunology at National Jewish Health. His principal research is in T cell biology, a subject he collaborates on with his wife Philippa Marrack.Rennie, J. (1992) Profile: Philippa Marrack and John Kappler – Keeping It In the Family, Scientific American 267(2), 43-44. In 1983 they discovered the T cell receptor, together with Ellis Reinherz and James Allison.
Awards 1986 – Appointed investigator, Howard Hughes Medical Institute 1989 – Elected member, National Academy of Sciences 1993 – Cancer Research Institute William B. Coley Award 1993 - Paul Ehrlich and Ludwig Darmstaedter Prize 1994 – Louisa Gross Horwitz Prize for Biology or Biochemistry (Columbia University) 2015 – Wolf Prize in Medicine
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