Saint John River or Saint Johns River may refer to:
Rivers Saint John River (Bay of Fundy), in Canada (mainly New Brunswick but also Quebec) and the United States (Maine) Saint John River (Liberia), in West Africa Saint Johns River (Grenada), in Grenada St. John's River (California), in Visalia, California, United States St. Johns River, in Florida, United States
Communities St. John River District, Grand Bassa County, Liberia
Education St. Johns River State College, a public college in Northeast Florida, United States
Utilities St. Johns River Terminal Company St. Johns River Water Management District
Transportation St. Johns River Light, decommissioned lighthouse in Florida, United States St. Johns River Shipbuilding Company, defunct company in Florida, United States St. Johns River Veterans Memorial Bridge, Florida, United States
See also Saint-Jean River (disambiguation) Johns River (disambiguation) John River St. John Rivers, a character in Jane Eyre Saint John's St. John River campaign St. John River expedition