Giselher, Gisilher, Gisiler, or Giseler () is a Germanic masculine given name. It may refer to:
Giselher of Burgundy, Burgundian king Gisilher (archbishop of Magdeburg) (died 1004), German ecclesiastic Giselher Klebe (1925–2009), German composer Giselher Schubert (born 1944), German musicologist Giselher Wilke (1922–2007), German army officer Giselher Wirsing (1907–1975), right-wing German journalist, author, and foreign policy expert
See also Gislhere (died circa 785), English Bishop of Selsey Jan Jerzy Gisiler, 18th century Polish military officer