Megaspiridae is a family of air-breathing land snails, terrestrial pulmonate gastropod mollusks in the superfamily Orthalicoidea (according to the taxonomy of the Gastropoda by Bouchet & Rocroi, 2005).Breure A. S. H. & Romero P. (2012). "Support and surprises: molecular phylogeny of the land snail superfamily Orthalicoidea using a three-locus gene analysis with a divergence time analysis and ancestral area reconstruction (Gastropoda: Stylommatophora)". Archiv für Molluskenkunde: International Journal of Malacology 141(1): 1-20. .
The family Megaspiridae has no subfamilies.
Genera Genera within the family Megaspiridae include: Callionepion Pilsbry & Vanatta, 1899 Koltrora Simone, 2024 Kora Simone, 2012 Megaspira Lea, 1838 - type genus of the family Megaspiridae Paeniscutalus Wurtz, 1947 Thaumastus Albers, 1860Breure A. S. H. & Borrero F. J. (2008). "An annotated checklist of the land snail family Orthalicidae (Gastropoda: Pulmonata: Orthalicoidea) in Ecuador, with notes on the distribution of the mainland species. Zootaxa 1768: 1-40. abstract. - synonym: Tholus Strebel, 1909Abbott R. T. (1989). Compendium of Landshells. American Malacologists, Inc., Melbourne, Florida. Breure A. S. H. (1979). "Systematics, phylogeny and zoogeography of Bulimulinae (Mollusca)". Zoologische Verhandelingen Leiden 168: 1-215, figs 1-182, pls. 1-3, tables 1-5. PDF.
Synonyms Orphnus Albers, 1850: synonym of Thaumastus E. von Martens, 1860 (junior homonym, invalid: not McLeay, 1819) Pachytholus Strebel, 1909: synonym of Thaumastus E. von Martens, 1860 (junior subjective synonym) Pyrgelix H. Beck, 1837: synonym of Megaspira I. Lea, 1836 Tatutor Jousseaume, 1887: synonym of Thaumastus E. von Martens, 1860 Tholus Strebel, 1909: synonym of Thaumastus E. von Martens, 1860
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