St. Alphonsus Church may refer to:
Church of St Alphonse Liguori, Birkirkara, Malta Novena Church, Singapore (officially the Church of Saint Alphonsus)
Italy Church of St. Alphonsus Liguori, Rome, Italy Santa Maria della Mercede e Sant'Alfonso Maria de' Liguori, in the historic center of Naples, Italy
United Kingdom Our Lady and St Alphonsus Church, Worcestershire, England
United States Saint Alphonsus Church, New Orleans, Louisiana National Shrine of St. Alphonsus Liguori, in the Archdiocese of Baltimore, Maryland, United States St. Alphonsus Liguori Catholic Church (St. Louis), Missouri St. Alphonsus Ligouri Church (New York City)