Otomo, or Ōtomo, is a Japanese surname. Otomo may also refer to:
Otomo (automobile), automobile produced between 1924–1927 Otomo (comics), character in the Marvel Comics universe Otomo (film), a 1999 German film Ōtomo clan, a samurai clan Otomo Station, train station in Iwate Prefecture, Japan 3911 Otomo, Main-belt asteroid Otomo, a fictional character in RoboCop 3 Otomo, a song by Bonobo from the album Fragments