UCE may refer to:
Science and technology Ultra-conserved element, a type of conserved sequence of DNA Unsolicited commercial email, a kind of email spam
Universities University of Central England, now Birmingham City University Universidad Central del Ecuador (Central University of Ecuador), a national university in Ecuador Universidad Central del Este (Eastern Central University), a private institution in the Dominican Republic University College of Engineering (disambiguation)
Other uses Uganda Certificate of Education, a certificate awarded for completion of secondary school in Uganda (Communist Unification of Spain), a Spanish political party
See also University College of Engineering, Kakatiya University (KUCE), Kothagudem, India