George Manning may refer to:

George Manning (died 1849), British murderer, the husband and accomplice of Marie Manning George Manning (New Zealand politician) (1887–1976), Mayor of Christchurch, New Zealand George T. Manning (1908–1956), New York politician

See also George Manning McDade (1893–1966), Canadian politician Gwyn Manning (1915–2003), Welsh footballer who played at the 1948 Summer Olympics, sometimes mistakenly listed as George Manning