Benacerraf ( Ben-Aseraf) is a surname. Notable people with the surname include:

Baruj Benacerraf (1920–2011), Venezuelan immunologist Beryl Benacerraf (1949–2022), American radiologist and obstetrics researcher Margot Benacerraf (1926–2024), Venezuelan film director Paul Benacerraf (1930–2025), French-born American philosopher

See also Benacerraf's epistemological problem Benacerraf's identification problem