Bouthillier is a surname, and may refer to:
Armand Jean le Bouthillier de Rancé (1626–1700), French Trappist monk Claude Bouthillier (1581–1652), French statesman and diplomat Flavien-Guillaume Bouthillier (1844–1907), Quebec lawyer and politician Guy Bouthillier (born 1939), Canadian academic John Le Bouthillier (1797–1872), Quebec businessman Léon Bouthillier, comte de Chavigny (1844–1907), French statesman Louis-Tancrède Bouthillier (1796–1881), Canadian merchant Marie-Claude Bouthillier (born 1960), Canadian artist Victor Le Bouthillier (1590–1670), French politician and clergyman Wilfred Le Bouthillier (born 1978), Canadian singer Yves Bouthillier (1901–1977), French politician