Wayne Arthurs was the defending champion, but did not participate that year.
James Blake won the title, defeating Lleyton Hewitt 7–5, 2–6, 6–3 in the final.
Seeds
Lleyton Hewitt (final) Nicolas Kiefer (second round, withdrew because of an illness) Tommy Robredo (quarterfinals) Robby Ginepri (first round) James Blake (champion) Gaël Monfils (first round) Tommy Haas (withdrew because of a shoulder injury) Fernando Verdasco (first round)
Draw
Finals
Top half
Bottom half
External links 2006 Tennis Channel Open Draw 2006 Tennis Channel Open Qualifying Draw