Newhook is an English surname. Notable people with the surname include:
Abby Newhook (born 2003), Canadian ice hockey player Alex Newhook (born 2001), Canadian ice hockey player Cle Newhook (1943–2018), Canadian Anglican priest and politician Frank Newhook (1918–1999), New Zealand botanist Hazel Newhook (1914–2016), Canadian politician Jim Newhook (1915–1997), New Zealand veterinary academic