Mazzoni is an Italian surname. The earliest members of the Mazzoni listed here hailed from either Emilia-Romagna or its western neighbor Tuscany in the 15th century. Other (and less notable) members have been consistently recorded in the Serchio River Valley of Tuscany – especially in the vicinity of Barga – since the 16th century.

Surname Alfredo Mazzoni, Italian professional football player and coach Angelo Mazzoni, Italian Olympic fencer Angiolo Mazzoni, Italian architect Antonio Maria Mazzoni, Italian composer Carlo Mazzoni, Italian actor Cesare Mazzoni, Italian painter Corrado Mazzoni (1892–1917), Italian World War I lieutenant Cory Mazzoni, American professional baseball pitcher Dave Mazzoni, American film director, producer, and screenwriter Emiliano Mazzoni, Italian astronomer Erminia Mazzoni, Italian politician Giuliana Mazzoni, Italian psychologist and researcher Giuliano Mazzoni, Italian rally driver Giulio Mazzoni, Italian painter and stuccoist Guido Mazzoni (poet), Italian poet and professor Guido Mazzoni (sculptor), Italian sculptor Guy Mazzoni, French chess player Isabella Discalzi Mazzoni, Italian sculptor, active late 15th century Jacopo Mazzoni, Italian philosopher Javier Mazzoni, Argentine soccer player Kerry Mazzoni, American politician Luca Mazzoni, Italian soccer player Marco Mazzoni, Italian artist Margherita Pavesi Mazzoni, Italian painter, sculptor and poet Peter Mazzoni, American physician Pier Luigi Mazzoni, Archbishop of Gaeta Roberto Mazzoni, Italian sports shooter Sebastiano Mazzoni, Italian painter Torquato Mazzoni (1824 – after 1869), Italian painter Vittorio Mazzoni, Italian physiologist, discoverer of Mazzoni's corpuscles and joint discoverer of Golgi-Mazzoni bodies Vittorio Mazzoni della Stella (born 1941), Italian politician

Fictional people Apothecary Mazzoni, a character in The Flame and the Arrow