Desautels is a surname. Notable people with the surname include:
Gene Desautels (1907-1994), American baseball player Guillaume Desautels (1529-1599), French poet L. Denis Desautels (born 1943), former Auditor General of Canada Michel Désautels (born 1951), Canadian writer and journalist Richard G. Desautels (1932-1951), United States Army soldier
See also Janette Desautel, a fictional chef in the HBO television series Treme