D22 may refer to:
Ships General Moran, an Almirante Clemente-class destroyer of the Venezuelan Navy , a Fletcher-class destroyer of the Hellenic Navy , a W-class destroyer of the Royal Navy and Royal Australian Navy , a Battle-class destroyer of the Royal Navy , a Fletcher-class destroyer of the Spanish Navy
Other uses D22 road (Croatia) Darmstadt D-22, a German sport plane Dublin 22, a postal district in Ireland Kelantan State Route D22, now Malaysia Federal Route 196 LNER Class D22, a class of British steam locomotives Nissan Navara, a pickup truck