Andrew Bruce may refer to:

Andrew Bruce (athlete) (born 1958), athlete from Trinidad and Tobago Andrew Davis Bruce (1894–1969), former Major General and President of the University of Houston Andy Bruce (born 1964), Scottish former professional football player Andrew A. Bruce (1866–1934), North Dakota Supreme Court justice Andrew Bruce (bishop) (1630–1699), Scottish bishop Andrew Bruce, 11th Earl of Elgin (born 1924), Scottish nobleman