Frank Barnes may refer to:
Frank Barnes (left-handed pitcher) (1900–1967), American baseball pitcher Frank Barnes (right-handed pitcher) (1926–2014), African American baseball pitcher Frank Barnes (actor) (1875–after 1949), American actor Frank Barnes (politician) (1904–1952), Australian politician Frank C. Barnes (1918–1992), American lawyer, author and cartridge designer
See also Honey Barnes (1900–1981), American baseball catcher Francis Barnes (disambiguation) Frank C. Barnes House in Portland, Oregon, U.S.