William Powlett may refer to:

Lord William Powlett (c.1663/7–1729), British politician who represented Lymington and Winchester William Powlett (MP) (c.1693–1757), son of the above, British politician who represented Lymington, Winchester and Whitchurch William Vane, 3rd Duke of Cleveland (1792–1864), British politician known as "Lord William Powlett" from 1809 to 1864 William Powlett Powlett, English landowner and politician Lord William Paulet (1804–1894), British field marshal See also William Orde-Powlett, 5th Baron Bolton